What Baby Teeth Can Teach Us About Prenatal Care – A Research Update from Dr. Richard Frye
Dr. Richard E. Frye walks through research that reads a pregnancy out of a baby tooth, showing atypical fetal inflammatory regulation in autism. Paper: Dumitriu et al., "Deciduous Tooth Biomarkers Reveal Atypical Fetal Inflammatory Regulation in Autism Spectrum Disorder," iScience 2023.
A Systematic Review of Folate and the Human Enteric Microbiome: Biological Mechanisms and Clinical Implications
Richard E. Frye MD, PhD
Editorial: Early Metabolic Drivers of Neurodevelopmental Disorders: Potential Pathways to Early Detection and Novel Interventions
Richard E. Frye MD, PhD
Mitochondrial dysfunction can connect the diverse medical symptoms associated with autism spectrum disorders
Frye, R., Rossignol, D. Mitochondrial Dysfunction Can Connect the Diverse Medical Symptoms Associated With Autism Spectrum Disorders. Pediatr Res 69, 41–47 (2011).
Substantial problems with measuring brain mitochondrial dysfunction in autism spectrum disorder using magnetic resonance spectroscopy
Rossignol, D.A., Frye, R.E. Substantial Problems with Measuring Brain Mitochondrial Dysfunction in Autism Spectrum Disorder Using Magnetic Resonance Spectroscopy. J Autism Dev Disord 42, 640–642 (2012). https://doi.org/10.1007/s10803-011-1276-z
Mitochondrial Dysfunction in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis
Rossignol, D., Frye, R. Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis. Mol Psychiatry 17, 290–314 (2012). https://doi.org/10.1038/mp.2010.136
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder
Frye, R., Melnyk, S. & MacFabe, D. Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder. Transl Psychiatry 3, e220 (2013). https://doi.org/10.1038/tp.2012.143e
Redox Metabolism Abnormalities in Autistic Children Associated with Mitochondrial Disease
Frye, R., DeLaTorre, R., Taylor, H. et al. Redox metabolism abnormalities in autistic children associated with mitochondrial disease. Transl Psychiatry 3, e273 (2013). https://doi.org/10.1038/tp.2013.51
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